By DEE-ANN DURBIN

The debate over whether Coca-Cola should use high-fructose corn syrup or cane sugar in its signature soda obscures an important fact: Consumers are increasingly looking for Coke with no sugar at all.

Coca-Cola Zero Sugar, which was introduced in 2017, uses both the artificial sweetener aspartame and the natural sweetener stevia in its recipe. It’s one of Coke’s fastest-growing products, with global case volumes up 14% in the first quarter of the year. By comparison, the company’s total case volumes were up 2%.

PepsiCo also noted Thursday that 60% of its sales volumes in major markets in the second quarter came from low- or no-sugar drinks.

“When you look at colas, the percentage of growth coming from zero sugar is significant,” said Duane Stanford, the editor and publisher of Beverage Digest.

Coca-Cola Co. hasn’t confirmed a presidential pronouncement

The scrutiny over Coke’s sweeteners began Wednesday, when President Donald Trump announced that Atlanta-based Coca-Cola Co. had agreed to switch to using cane sugar in the regular version of its beverage manufactured in the U.S.

“I have been speaking to Coca-Cola about using REAL Cane Sugar in Coke in the United States, and they have agreed to do so,” Trump wrote on his social media site. “I’d like to thank all of those in authority at Coca-Cola. This will be a very good move by them — You’ll see. It’s just better!”

Coca-Cola didn’t confirm the change. In a statement, the company said it appreciated Trump’s enthusiasm and would share details on new offerings soon.

Stanford said he doubts Coca-Cola will fully shift away from high fructose corn syrup, which has sweetened Coke in the U.S. since the 1980s. There would be tremendous supply chain and logistics headaches, he said, and the U.S. doesn’t make enough sugar for Coke’s needs.

He expects the Atlanta-based company will offer a cane sugar-sweetened version in the U.S. just like its rival Pepsi has been doing since 2009. He noted that Coke has indulged U.S. fans by importing Mexican Coke, which is made with cane sugar, since 2005. Coke positions Mexican Coke as an upscale alternative and sells it in glass bottles.

A rush to defend high fructose corn syrup

The corn industry wasn’t happy with the speculation. In a statement Wednesday, Corn Refiners Association President and CEO John Bode said replacing high fructose corn syrup with cane sugar makes no sense and would cost thousands of American manufacturing jobs.

Shares in ADM, a maker of high fructose corn syrup, dipped nearly 2% Thursday after Trump’s announcement.

In a message on X, Coca-Cola defended high fructose corn syrup, saying it’s no more likely to contribute to obesity than table sugar or other full-calorie sweeteners.

“It’s safe; it has about the same number of calories per serving as table sugar and is metabolized in a similar way by your body,” the company said. “Please be assured that Coca-Cola brand soft drinks do not contain any harmful substances.”

The Food and Drug Administration also says there is no evidence of any difference in safety among foods sweetened with high fructose corn syrup and those that sugar, honey or other traditional sweeteners.

US consumers are seeking more options

Soft drink preferences are highly subjective, as anyone who has been in a Pepsi vs. Coke or 7-Up vs. Sprite debate knows. But recent trends indicate that Coke and other drink makers need to focus on the kinds of low- and no-sugar drinks that a growing number of consumers are seeking, according to Stanford.

He said his data shows original Coke was the top seller by volume in the U.S. last year, with 19% market share, while Coke Zero Sugar was seventh and had a 4% market share. But Coke Zero Sugar’s share grew 10%, while original Coke’s share was flat.

Paige Leyden, the associate director of food service, flavors and ingredients reports at the market research company Mintel, said drinks with a health halo like Olipop — which has 1 gram of sugars compared to original Coke’s 65 grams — are also pressuring legacy soda makers. Mintel expects full-sugar sodas will see a 3.4% rise in U.S. sales this year, while diet sodas will see 11.8% growth.

Still, nutritionists suggest avoiding added sugars, no matter the form, since they provide empty calories with no nutrients. The 2020 U.S. dietary guidelines advise people to limit foods and beverages higher in added sugars, and say children under 2 should not be fed them at all.

Health Secretary Robert F. Kennedy, whose nutrition views often diverge from mainstream nutrition science, has spoken out against sugar. His agency is expected to release updated nutrition guidelines later this year.

“There’s things we’ll never be able to eliminate, like sugar,” Kennedy said at an April news conference. “And sugar is poison, and Americans need to know that.”

Aspartame and other artificial sweeteners are also named as a concern in a government report Kennedy issued in May.

AP Health and Science Editor Jonathan Poet contributed from Philadelphia.